Map the gene set of interest to the known pathways

Map2Pathways(
  partcorr.list,
  conditions = NULL,
  GeneInterest = NULL,
  pathwayRef,
  pathwayRef_geneVariable,
  pathwayRef_pathVariable,
  threshold = 0
)

Arguments

partcorr.list

a list of estimated partial correlation matrices

conditions

a vector of the names of the corresponding partial correlation matrices

GeneInterest

character. e.g. "MYC"

pathwayRef

a data frame, including the gene and pathway information. e.g. column1 is genes, column2 is the pathways this gene belongs to according to Sigma.Mini.Map

pathwayRef_geneVariable

character, the column name of gene variable

pathwayRef_pathVariable

character, the column name of pathway variable

threshold

the cutoff value for partial correlation, for visualization and GSEA purpose.

Value

x.connect: the list of genes that connected to the GeneInterest under each condition

GSEA.table: the final GSEA table