Map scRNA-seq counts to a known covariance structure

Map scRNA-seq counts to a known covariance structure

CountMap(sigma, ngene, n, a1 = 3, b1 = 1, a20 = 2, b20 = 3, a30 = 1, b30 = 10)

Arguments

sigma	a covairance matrix
ngene	number of genes
n	number of samples
a20	the hyperparameter for generating beta, where beta~Gamma(a20,b20)
b20	the hyperparameter for generating beta, where beta~Gamma(a20,b20)
a10	the hyperparameter for generating alpha, where alpha~Gamma(a10,b10)
b10	the hyperparameter for generating alpha, where alpha~Gamma(a10,b10)
a3	the hyperparameter for generating pij, where pij~beta(a3, b3)
b3	the hyperparameter for generating pij, where pij~beta(a3, b3)

Value

a list of i) raw count data matrix; ii) adjacency matrix; iii) the true expression mean level theta matrix; iv) zij: the dropout matrix; v) sigma: the covariance matrix; vi) precision: the precision matrix.